Each of Alex's illustrated layers represent part of the process of treatment including diagnosis, imaging, histology for tumor cell type, neoadjuvant therapy - before surgery, chemotherapy (showing apoptosis of a cancer cell) and targeted therapy with monoclonal antibodies. She says "This magazine is targeted at Advanced Practitioners and is focusing on all the points of contact between practitioner and patient ...The steps are shown going from a macro to micro level, the patient, the tumor, the cell type, decreasing blood supply to the cancer cells, death of individual cells, and therapies that target a sub-cellular level."